Clinical education & evidence platform for UK primary care clinicians.

One patient, three pains: a palliative care case study in opioid titration

This week, our expert insights will guide you through a case study from Jan Brassington’s webinar, ‘Managing Pain in Palliative Care.’ You can now watch it as an on-demand video on our CPD Webinars page!

MHRA tightens the warnings on 5-ARIs / DHT blockers

Medicine Central | Clinical Update. Safety warnings from MHRA on the use of 5-alpha reductase inhibitors, sometimes referred to as DHT blockers.

Unseen in primary care: how patients with complex mental health difficulties experience accessing help

Around a quarter of patients presenting to primary care with mental health difficulties meet criteria for personality disorder, yet only 1 to 1.5% have a coded diagnosis. A new qualitative study explores what that gap looks like from the patient side.

Primary Care Research: From an Optional Extra to an Essential Part of Modern General Practice

Almost 90% of NHS patient contacts happen in primary care, yet most research still happens somewhere else. Dr Fatima Tahir on why that gap matters, and what practices stand to gain from closing it.

AI scribes and the changing shape of clinical documentation

Dr Frederick Reynolds, a GP using ambient scribes day-to-day, has written the kind of thoughtful, first-hand review these tools deserve.

Falling blood pressure and BMI in T2D may signal early dementia

Fish oil and dementia prevention: what a new high-dose DHA trial found

A new randomised trial (PreventE4) confirmed that high-dose DHA supplementation reaches the brain — even in APOE ε4 carriers — but found no measurable benefit on hippocampal volume, cortical thickness, or cognitive scores over 24 months.

ADHD prescribing in primary care: what GPs need to know

Rising ADHD referrals means more GPs managing shared-care stimulant prescribing. This week's article is a GP guide to shared-care monitoring, red flags and drug interactions, with a free downloadable cheat sheet.

The no-biopsy pathway has arrived, and it stops at the surgery door

State of Child Health 2026

AI in elderly care: two problems nobody is talking about together

AI is arriving in care homes — wearables, fall sensors, pain recognition apps. The potential is real. But two compounding problems are not getting enough attention: the data gap and the deployment gap.

Statins past 80: what does the evidence actually say?

At what age do you stop offering statins for primary prevention? It's a question the guidelines can only partially answer.

MART versus conventional ICS/LABA plus SABA: does switching actually change outcomes?

Across 19 papers published since 2022, a consistent picture emerges on MART versus conventional ICS/LABA plus SABA. The headline benefit is concentrated in exacerbation prevention - but the size of the gain depends heavily on baseline exacerbation risk.